Sentence examples for subjects phenotype from inspiring English sources

Conversely, tetramer-specific CD8 T-cells from TB patients contained higher proportions of cells with an effector memory-like (15% in TB patients versus 5% in LTBI subjects) and a central memory-like (10% in TB patients versus 3% in LTBI subjects) phenotype; however, also the frequencies of these two memory subsets did not change significantly before and after therapy.

Interestingly, subjects' phenotype for CYP2D6 differentially modulated the tamoxifen effect on Ki-67 and SHBG, showing an enhancement of activity in the extensive phenotype subjects.

The GWAS consisted of 5,861 Icelandic subjects phenotyped for hip (HBMD) and spine (SBMD) BMD and genotyped at 301,019 SNPs (Styrkarsdottir et al. 2008).

Detailed information on subjects, phenotyping, de novo genotyping and QC procedures in the TEENAGE cohort can be found in Supplementary Material.

Models developed using clinical variables only were less accurate (C-statistics 0.543 – 0.687).> To assess the influence of the subjects' phenotypes on model accuracy we performed additional analyses.

Models 1 and 4 directly correspond to the organization of the biological experiment, where the sample [considering Model 1, Equation (3)] represents expression of m genes in G measured for n independent subjects, together with the subjects phenotypes.

On the other hand, the relationship we found seems to be independent of subject phenotype.

Another trial, which was open label, using a different subject phenotype including those with neurogenic OAB, found a beneficial effect of 50 nM RTX [ 120].

In cases where a healthy subject phenotype does not represent target population or explain the variability, a PBPK model may be used to inform design to obtain additional sparse PK data from efficacy/safety trials, which can supplement existing data.

"This allows subject phenotyping and tissue sampling to be brought into research labs to do the high-technology work that reflects today's bioscience".

Table 5 shows the lack of Ki-67 modulation in the no tamoxifen treated subjects by phenotype, and the significant tamoxifen - phenotype interaction (P = 0.01).