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Individual subjects' phase lag shows a substantial variation.
The remaining one-third were typically larger (>200 subjects) phase II or III trials, but, disappointingly, only fewer than one-half of these administered neuroprotective therapy within the 4 6 h therapeutic window within which efficacious neuroprotection is considered to be achievable.
A difference between the no-noise and an added-noise condition in which most subjects' phase locking values did not differ from zero in the added-noise condition would be meaningless.
To validate the predictive capability of these models, we cultured PBMCs from 20 new subjects (phase 2).
One of the main obstacles for translation of treatments to improve function with aging lies in the initial steps from assessments in animal models to testing for safety and efficacy in human subjects (phase I and II clinical trials).
A prospective, observational, populational, multicentre study will be carried out with a 12-month follow up divided into three phases: Phase I, initial evaluation with diagnostic confirmation and baseline evaluation of the study subjects; Phase II with a 12-month follow up to observe the appearance of episodes influencing an exacerbation and Phase III, the final evaluation.
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In female subjects phases of the menstrual cycle were controlled.
After the study phase, subjects completed one of the 10-minute filler tasks described above.
Some teaching job sites, such as Guardian Jobs for Schools, allow you to save your job search preferences by region, town and city, subject, phase and school type – and will send automatic email alerts of the latest vacancies.
In brief, for each subject, phase synchrony was computed for the PCA-derived signal in a distinct frequency f0 of his/her maximal gamma activity (f0±3 Hz; see also [18]) extracting the phase values by means of Morlet wavelet analysis.
Interestingly, there was no correlation across the 12 HPC-lesioned subjects between phase 2 and phase 4 in terms of percentage HR choices.
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