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Finally, successful preliminary in-vivo experiments were carried out on live pig models to verify the feasibility of the patient-specific CAD methodology based on the subjects' imaging data.
In order to avoid learning effects, the order of drug administration was counterbalanced, and the subjects, imaging staff and analysis team were blinded to drug condition.
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Our institutional review board approved the in vivo subject imaging.
The matching difficulty under various skin appearances of different subjects and imaging distortion is also analyzed.
Using only one image for expression recognition needs robust and highly distinctive features to cope with variations in human subjects or imaging conditions[3].
Written informed consent was obtained from all subjects before imaging.
VA imaging was attempted on all subjects; seven imaging attempts failed because of various technical reasons, and data from these patients were excluded from the study.
All subjects underwent imaging with an Imatron C-150 scanner (GE Imatron, now part of GE Healthcare, Little Chalfont, Buckinghamshire, UK) as described previously [ 6].
All females subjected to imaging in this study were nulliparous.
The results of phantom study demonstrated that the radioactive OI could be used for living subject imaging because of its high spatial resolution.
Additional developments focusing on blocking stray light were successful and permitted a normal subject imaging exam.
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