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Conversely, the role of the genetic predisposition to BC could not be demonstrated in a smaller and more heterogeneous pool of 201 subjects characterised by a cancer FH, including cancer patients and healthy subjects.
1300 SSc cases (961 white, 178 black and 161 Hispanic subjects) characterised for clinical skin forms (limited vs diffuse), SSc-specific autoantibodies (anticentromere (ACA), anti-topoisomerase I (ATA), anti-RNA polymerase III (ARA), anti-U3 ribonucleoprotein (fibrillarin)) and others were studied using molecular genotyping.
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We then had the subjects characterise the following features of this novel set of landmarks: Salience (' To what extent does this item grab your attention?' ; 5 point scale: 1 = Not at all… 5 = Very much).
Kirkup's later poetry became richly varied in both form and subject, characterised by an impressive openness to new possibilities.
Alongside the bells and whistles of media-making software, the challenge remains to find reliable, up-to-date information in a subject characterised by constant change and rapidly outdated material.
Compared to controls, the case subjects were characterised by a higher frequency of nulliparity (31 vs 23%, P=0.09), a higher frequency of history of breast biopsy (28 vs 22%, P=0.05), a higher median weight (68.1 vs 63.6 kg, P=0.002), and higher median body mass index (25.7 vs 24.3 kg m−2, P=0.007).
The study characterises 36 healthy Caucasian subjects of Swiss descent.
At the level of genera, the asthmatic subjects were characterised by excess of Haemophilus spp. (Pc<10−12) and Staphylococcus spp. (Pc<10−2), whereas Prevotella spp. were more frequent in controls (Pc<10−30).
Lipodystrophic subjects are characterised by an elevated REE and LM.
Subjects were characterised in regard to HTLV-1 infection as either symptomatic patients (SP) or as ACs.
Practically, haplotypes can be inferred by LD analysis of a region in unrelated subjects, or characterised molecularly in family pedigrees (see Figure 1 ).
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