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The hyperglycemic experiments in healthy subjects were terminated 4 h after meal ingestion.
No subjects were terminated from the study due to non-fatal adverse events.
One study site with 30 subjects was terminated prematurely because of data-quality concerns; the efficacy and safety data for 100 subjects (excluding those from the terminated site) are presented in this analysis.
Four severity strata, including no neuropathy, mild neuropathy, moderate neuropathy, and severe neuropathy, were graded according to the score quartiles, and accrual of subjects into the study was terminated only when the smallest stratum contained 50 subjects.
Infusion of 25 and 50 mg amitriptyline appears to be well tolerated; however, the study was terminated when 1 subject in the 100-mg group developed severe bradycardia.
The study was terminated if the subject was moved out of NCCU for more than 2 hours.
The study was terminated early after 19 subjects enrolled.
The study was terminated.
The study is terminated.
The study was terminated early.
It is important that, where a rightholder excludes the application of such mechanisms or of such exception or limitation to one or more works or other subject matter, any ongoing uses are terminated within a reasonable period, and, where they take place under a collective licence, that the collective management organisation once informed ceases to issue licences covering the uses concerned.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com