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Our institutional review board approved the in vivo subject imaging.
The results of phantom study demonstrated that the radioactive OI could be used for living subject imaging because of its high spatial resolution.
Materials testing, phantom experiments, and normal subject imaging were performed on a combined NIRST/DBT system.
Additional developments focusing on blocking stray light were successful and permitted a normal subject imaging exam.
Healthy volunteers drawn from researchers and employees at our institution without known ocular pathology other than ametropia were asked to participate in subject imaging.
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Finally, successful preliminary in-vivo experiments were carried out on live pig models to verify the feasibility of the patient-specific CAD methodology based on the subjects' imaging data.
In order to avoid learning effects, the order of drug administration was counterbalanced, and the subjects, imaging staff and analysis team were blinded to drug condition.
In many instances, ACRIN uses the traditional paired design of diagnostic trials which dictates that each subject receive imaging examinations by all the technologies under study.
The overall advantage of truly simultaneous PET/MRI is that the same subject undergoes imaging at the same time with identical environmental parameters and stimuli.
All females subjected to imaging in this study were nulliparous.
The present study however shows that using ANCOVA would not be advisable as the covariate interacts with the within-subject imaging conditions.
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