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Colors of bars indicates subgroups of lines: black for O. rufipogon, orange for indica, green for tropical japonica, dark blue for temperate japonica with the qSH1-Kas allele, and light blue for temperate japonica with the qSH1-Nip allele.
Being able to make such subdivisions is important not only for specifying the functions perturbed in individual lines, but also for identifying subgroups of lines that are more likely to have a homogenous mechanism of action and thus a common set of affected fru M-expressing neurons.
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The two groups in Q are mutually exclusive after maximizing P. The lines in T are subgroups of the lines in Q, that is, they are only computed when there are enough remaining components after maximizing Q.
mRNA expression profiles of most tamoxifen-resistant cell lines were strikingly similar, except for the subgroups of cell lines in which NCOR2 or CITED2 were targeted by the retrovirus.
The measure of population differentiation, FST, averaged 0.139 among the subgroups of improved lines (Additional file 1: Table S1).
Nutlin-3 hardly induced apoptosis in our panel of wild-type p53 cell lines, which has been observed by others as well in a subgroup of cell lines (Tovar et al, 2006).
In the A1 subgroup, the breakdown of lines was as follows: 2% BAJIM, 5% CM, 64% CML, 5% HKI, 2% HPLET, 8% PANT, and 2% BML.
Molecular studies, in combination with unsupervised clustering methods, defined three subgroups of patient cell lines – M group with mtDNA mutation and N1 and N2 groups with nuclear defect.
Subgroup of each line was determined by the membership probability (Pritchard et al. 2000).
In particular, M-CAM expression identifies a subgroup of front-line therapy-responding patients who undergo dramatic relapses [45].
The authors reported the presence of a subgroup that largely consisted of lines developed from LaPosta Sequía.
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