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These results may explain the better power of linkage analysis using this "subgroup" strategy.
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Furthermore, within the prevailing 'biological' domain, the overlap of subgrouping strategies within the orthopaedic examination remains unexplored.
Herein, we suggest a subgroup classification strategy based on the cell origin rather than morphology features, e.g., EpCAM+ H-ChC.
One hipster subgroup's strategy is to disparage others as "liberal arts college grads with too much time on their hands"; the attack is leveled at the children of the upper middle class who move to cities after college with hopes of working in the "creative professions".
Briefly, the subgroup identification strategy was highly similar to that originally described by Perou et al. in 2000 [ 1].
The subgroup testing strategy is shown to be useful in detecting treatment effect in terms of power and control of study-wise error.
For the ACS subgroup, a strategy of increasing the catheterization rate is associated with a cost per QALY of less than $50,000, a willingness-to-pay threshold commonly proposed as reasonable value for money [ 24], in 56.3% of the simulations.
In supplementary work, we assessed the subtyping accuracy using our subgroup-specific strategy as a function of the sample size of the prototypic subgroup, shown for the basal subgroup in Additional file 4: Figure S3.
A randomised controlled trial of four management strategies for dyspepsia: relationships between symptom subgroups and strategy outcome.
Subgroup-specific strategy for molecular subtype assignment in a triple-negative breast cancer study cohort for the expression of gene SLC39A6.
Subgroup-specific strategy for molecular subtype assignment in an ER-positive study cohort (Trondheim set) demonstrated for a single gene, ESR1.
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