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Along with calculating subgroup effects, corresponding confidence intervals and standard errors were also computed.
The aim of this model was to show all the subgroup effects "at a glance".
Within each hypothesis, we designed three different subgroup effects scenarios where resulting subgroup rates are linear, flat, or nonlinear.
If important subgroup effects are anticipated, trials should either be powered to detect them reliably or pooled analyses of several trials should be undertaken.
The subgroup effects of the five remaining gene-gene interactions are further explored in Table 4.
There was also no evidence of effect modification by selected breast cancer risk factors or subgroup effects, including menopausal status.
The BDKRB2 C58T x ACE I/D interaction shows non-significant subgroup effects in the unadjusted model and one significant subgroup effect only after adjustment for covariates.
We were unable to explain all the heterogeneity between studies and we may have failed to identify subgroup effects due to lack of power.
Future studies should examine subgroup effects.
Subgroup effects will be explored using interaction tests.
The evidence suggests that interventions often resulted in specific subgroup effects.
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CEO of Professional Science Editing for Scientists @ prosciediting.com