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subfunctionalization
noun
The independent specialization of the two gene copies formed by duplication
Exact(60)
Accelerated gene evolution and subfunctionalization in the pseudotetraploid frog Xenopus laevis.
The duplication of this progenitor was followed by subfunctionalization of gene expression to give rise to tissue-specific c-Myb and A-Myb genes.
The duplication and divergence of the tandemly arrayed homeotic clusters have been studied in considerable detail and have provided evidence in support of the subfunctionalization model.
The major mechanisms by which duplicated genes are preserved in the face of purifying selection are thought to be neofunctionalization, subfunctionalization, and increased gene dosage.
As a corollary we find that the probability of subfunctionalization decreases exponentially fast as the population size increases.
These results suggest that the subfunctionalization of genes duplicated by polyploidy occurred in response to abiotic stress conditions.
Studies on cotton also showed that the subfunctionalization of genes duplicated by polyploidy occurred in response to abiotic stress conditions.
Recently, Lynch and Force have proposed a new explanation: subfunctionalization - after duplication the two gene copies specialize to perform complementary functions.
The possibility of subfunctionalization [37] cannot be, however, ruled out.
Another model predicts dividing the functions between the duplicate and the original copy (subfunctionalization) [22].
This residual enzymatic action can be explained by subfunctionalization of the duplicated genes.
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