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This could be because there were no subtype-specific clusters present, but it is also possible that our samples became too small for clusters to be detected when we subdivided the study population.
In exploratory analyses, we subdivided the study population according to their median C3c serum level at baseline and repeated the calculation of adjusted HRs and 95% CIs for incident type 2 diabetes (from Table 3) in both subgroups with low and high C3c at baseline (n = 617 and n = 634, respectively; Table 4).
We subdivided the study population according to the quintiles of pulse pressure, and the prevalence of proteinuria (≥1+) was compared by χ test among each group of the quintiles of pulse pressure separately in subjects with diabetes, prediabetes, or normal glucose tolerance, respectively.
The authors ascertained and subdivided the study sample (n=5225) based on measures of early development and of social environment, and examined candidate genes of monoamine neurotransmission, many of which have shown prior evidence of a gene environment interaction for affective disorders, namely SLC6A4, TPH2, COMT, MAOA and the dopamine receptor genes DRD1 DRD5.
We subdivided the study sample based on measures of early development arising from the fetal growth environment and neurological development during the first year of life (measure of early development) as well as from the family environment during pregnancy and early childhood (measure of social environment).
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We utilized point elevation data collected with a differential global positioning system to create a digital elevation model and derive slope and compound topographic index to subdivide the study area into landform element classes.
We test the hypothesis that this orogen-scale distribution correlates to the long-term evolution of the Alps by subdividing the study area into 37 square sub-areas (50×50 km), classified according to combinations of long-term exhumation and mean annual rainfall.
We stratified analyses by calendar period and attained age, and by subdividing the study region into areas north versus south of the Elbe river.
One approach subdivides the study into several (two or more) stages and combines the p-values of the different stages using Fisher's combination test.
In the two countries with available data from 1965 to 2007, further analyses were conducted subdividing the study period into two segments, 1965 1986 and 1987–2007.
Information about assets owned (other than domestic animals) was used to subdivide the study population into 5 quintiles of socioeconomic status.
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