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Most nonlinear programming algorithms are targeted to a particular subclass of problems.
This is particularly relevant for the subclass of problems in which we have access to the goal or to the highest value that a reward can take (e.g., reaching the center of a target, be as close as possible to a reference trajectory, etc).
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There exist problems for which the most efficient known decision algorithm has exponential time complexity in the worst case (and in fact are known to be \ \textbf{NP}\ -hard in the general case – see Section 3.2) but which operate in polynomial time either in the average case or for a large subclass of problem instances of practical interest.
The new method is much more efficient than previously derived RKN methods for some subclasses of problems.
We define a subclass of such problems, termed highly coupled variable topology multi-body (HCVTMB) problems, where configuration and relative geometric sizes cause meshing changes in one body to propagate throughout much of the model.
We present the empirical evaluation of a system, Augur, that makes use of EVP metaknowledge to adapt its own domain knowledge in the context of a particular subclass of classification problem called Compositional Classification.
Mathematical programs with equilibrium constraints (MPECs) form a relatively new and interesting subclass of nonlinear programming problems.
Minimum cost network design/dimensioning problems where feasibility has to be ensured w.r.t. a given (possibly infinite) set of scenarios of requirements form an important subclass of robust LP problems with right-hand side uncertainty.
Nonetheless, it is known that a significant subclass of \ \textbf{NP}\ -complete problems possess polynomial time approximation algorithms -- i.e. algorithms which are guaranteed to find a solution which is within a certain constant factor of optimality.
Moreover, while LOH (Hobs = 0) markers (with sufficiently low MAF to escape detection from HWE deviation) have been shown to cause false associations in transmission-disequilibrium tests (Hirschhorn & Daly 2005), here we demonstrated that the effect of near-zero Hobs is only a subclass of the larger problem of near-zero MGF in GWAS.
Further analysis also shows that some subclasses of the problem correspond to a single elementary landscape.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com