Sentence examples for subcellular locale from inspiring English sources
It may be that post-translational modification of RGS14 or Rap directly influences Rap/RGS14 interaction or directs these proteins to a distinct subcellular locale that facilitates their subsequent interaction [50], [51].
The rapid growth of high resolution and high sensitivity LC MS-based proteomics brought about the evoLC MS-basedBproteomicsprobroughtout enabout identheication of spevolutionofein tABPPts, their quantification and even subcellular locale.
This underscores the importance of where the Ca2+ is released, i.e., local versus global Ca2+ responses, and so we turned to identifying the molecular target of NAADP, and thereby its subcellular locale.
The asymmetric polarization of cells allows specialized functions to be performed at discrete subcellular locales.
KCNE1 had considerable overlap with HERG in all subcellular locales including on the surface.
The online software pSORTb [42] was used to predict subcellular locales using default settings for Gram negative bacteria.
Thus, our data suggest that Shroom3-Rock binding is required for directing Rock to specific subcellular locales.
Our results highlight the potential significance of PTEN itself as a scaffolding protein, rather than simply being the subject of scaffolding molecules that target its catalytic function to particular subcellular locales.
Based on the above data showing that Shroom3 variants R1838A and R1838C fail to bind Rock, we predicted that these mutants would also fail to recruit Rock to specific subcellular locales in vivo.
Shroom proteins bind directly to and recruit Rock to specific subcellular locales to regulate cell morphology and behavior (Dietz et al., 2006; Nishimura and Takeichi, 2008; Farber et al., 2011; Mohan et al., 2012).
The septin proteins play important roles in many cellular processes by providing rigidity to the cell membrane, serving as scaffolds to recruit proteins to specific subcellular locales, and creating membrane diffusion barriers to establish discrete cellular domains [ 8].
