The categories, subcategories, number of data points, number of genes, proteins, patients with data per subcategory and the number of studies are shown in Table 1.
Another limitation of the study is small sample size in subcategories of the data and further studies are required to reliably derive cutoffs.
Further, there was no significant difference in the prevalence of CVD, VTE, HT, DM2, and the subcategories of CVD and VTE (data not shown).
The data were analyzed using the GOTM [ 21] that generates a tree-like structure and yields two types of data: 1) the subcategories presenting statistical changes and 2) the hierarchy between these different subcategories.
However, only 4 trials contributed data on preterm birth [ 24, 26, 38, 39] and none of them presented data on subcategories of preterm birth.
In the initial phase, the researchers employed open coding that entertained all analytic possibilities to account for the data, and a coding that linked categories and subcategories of patterns that emerged from the data (Strauss and Corbin 1998).
The usgovernmentspending.com data classifies three subcategories of entitlement programs.
Data were extracted for countries with at least 3 years of data coded as C45 (ICD-10) or any of its subcategories.
In the final stage of data analysis, we manually sorted the codes into larger categories and subcategories (selective coding), and all codes were compared.
During coding and organization of data, memos were written to elaborate the categories and brainstorm ideas for possible themes to explain the data within subcategories.
