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Sub group analysis and meta-regressions were achieved in order to explore heterogeneity of the data.
But in the sub group analysis of the studies specific of septic patients (n=7), mortality was unaffected by RBCT (pooled OR was 1.10[0.75, 1.60]; I²=57%, p = 0.03).
The heterogeneity could be explained by the statistical methods (sub group analysis of the 11 studies with multivariate analyses: pooled OR=1.35[1.18-1.54]; I²=44%, p = 0.06)).
Sub group analysis among non smokers did not reveal any significant difference between the two groups.
We did not carry out a sub group analysis to decrease the heterogeneity between various studies.
A sub group analysis was carried out among non smokers of the study population.
Meaningful sub group analysis according to any criteria was limited by heterogeneity in other areas.
It is widely recognised that powering a sub group analysis can dramatically increase sample size requirement.
This sub group analysis was performed on ITT data as well as completers only.
These doses are based on a meta-analysis with sub group analysis for optimal dose for TENS [ 8].
If the interaction term was significant in Model 3, effect modification was assumed and sub group analysis was performed.
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