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Sub group analyses will be conducted by sex, BMI category and diagnosed chronic disease versus none.
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Finally, sub-group analyses were considered.
Sub-group analyses were also done.
Sub-group analyses were performed according to species (PA and Eb) and resistance for Eb.
Two sub-group analyses were performed by considering the type of intensive care unit admission (intra-abdominal surgery vs. other).
We did not conduct sub-group analyses on our population as we believe our trial, and most trials, are underpowered to provide appropriate sub-group analyses [15], [16].
Sub-group analyses for alendronic acid and risedronate sodium exposed individuals were planned a priori.
We conducted sub-group analyses, specified a priori, for alendronic acid (n = 1489) and risedronate sodium (n = 649) exposed patients.
No formal sub-group analyses are planned.
Sub-group analyses were also done after excluding underweight participants.
If significant interactions were found, sub-group analyses were performed.
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