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Recall bias which is one of the intrinsic limitations of any retrospective study was minimized by interviewing patients within two to four months of treatment outcome.
Hence, the selection bias in our study was minimized.
Bias within the study was minimized by including all cases of pressure ulceration with vitamin D levels within the cohort.
Selection bias in this study was minimized by random sampling and selection bias due to non-participation was considered negligible.
The number of mice used in this study was minimized for ethical reasons, and all procedures were performed in accordance with the guidelines for animal experimentation from the ethical committee of Kyoto University.
In addition, the controls were derived from the same cohort as the cases; thus, the potential selection bias that can occur with a conventional case control study was minimized.
Similar(53)
It is therefore likely that the effects of seasonal variation in the current study were minimized.
The discrepancy between the ANITA trial and our study is minimized when the chemotherapy scheme is included in the analysis.
We believe that typical types of bias derived from a retrospective study were minimized as much as possible.
Subsequently, the number of animals required to complete a given study is minimized, further ensuring the most efficient use of such a precious experimental animal.
The likelihood that these factors influenced the results obtained in the present study is minimized by the fact that chimaeras were not infected with S. aureus until 8 weeks post-transplant.
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