The consequence of alterations in the P53 target genes observed in this study are altered growth/proliferation and a potential failure to elicit appropriate responses to apoptotic-inducing stimuli, such as chemotherapy.
The results show that the expression of the IGF-axis members included in the present study are altered between tumour and normal, and indicate that the IGF-axis may be involved in hepatoblastoma development.
To determine whether the expression of genes identified in this study were altered by non-viral-mediated changes in SOX9 expression, we investigated in vitro cultures of freshly isolated human articular chondrocytes.
Therefore, study protocol was altered to allow metformin addition to sulfonylurea and sulfonylurea addition to metformin.
Although in our study MMSE was altered in patients with stage 3 of overt HE, but this can be detect clinically and generally requires no additional method.
Due to fluctuations in available resources, the study protocol was altered in May 2006, restricting the follow-up duration to 12 months post-delivery, but then extended to 18 months from January 2008 onwards [ 27].
For the second study, the game was altered so that children's ability to adopt a precautionary saving motive could be examined.
In that study, food intake was altered due to photoperiod, but did not correlate with adipose tissue leptin mRNA abundance [ 18].
In this study, ECM gene expression was altered by HFD in a time-dependent manner.
All the medical histories of the mere 12 children in Wakefield's study had been altered or misrepresented.
These errors require some corrections, which are listed below, but the authors state that none of the conclusions of their study have been altered by these revisions.
