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It is also possible to study tolerance of filtering techniques to ambiguity or inaccuracy of available a priori information in other ways.
As the MDM2 expression pattern in normal tissues is similar in humans and mice, we generated TCR transgenic mice to study tolerance mechanisms against this TAA.
In those study tolerance was achieved in mice naive to FIX.
In a similar study, tolerance to a cat dander allergen was achieved after 3 i.LN.
In our study, tolerance to exemestane was good and no patient withdrew because of the treatment's side effects.
In our study, tolerance heritability could not be estimated because the data included only one record per individual.
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In this study, tolerances of pressure and velocity components are set to 1E-3, while tolerance of gas and solid components are set to 1E-5, and energy equation to 1E-6.
In the present study tolerances were between 0.2 and 2 % which are within the range used in previous studies with no bias introduced with larger tolerance levels (Benstead et al. 2006; Cole et al. 2011; Duffy et al. 2011; Stenroth et al. 2006).
This protocol will be used in future to identify tolerant donors, for studying tolerance mechanisms and for evaluating breeding material.
Five decades ago Medawar and colleagues published an article in Nature [1] demonstrating that transplantation tolerance can be acquired; in these studies tolerance was strongly associated with donor leukocyte chimerism [1], [2].
The gopher-plant interaction is an especially appropriate system for studying tolerance because root herbivory directly affects the organs involved in resource acquisition and storage that would normally be enlisted in tolerance.
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