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A number of genes identified in this study to be affected by infection have not previously been associated with infection or are presently unidentified.
Larger studies in AA women are needed to further evaluate these issues, as well as evaluate the effect by "intrinsic" subtypes (luminal A, luminal B, basal-like and human epidermal growth factor receptor 2-positive/estrogen receptor-negative), which were suggested in one study to be affected differently by adiposity measures [ 36].
In order to make predictions of DNA curvature for the upstream regions of our affected genes, we used bend.it ® [ 29] to calculate predicted curvature in 500 bp regions upstream of the 54 genes shown by our study to be affected by berenil [ 30].
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Changes in root system architecture, biomass, and tissue composition, together with root exudate chemistry, which we have shown in previous studies to be affected by endophyte infection and fescue cultivar, likely explain these findings.
Since some interventions reported greater adaptive tendon responses than others, the outcome of the studies seems to be affected by differences of the applied loading conditions.
Hence, vole density in our study area seems to be affected by kestrel predation (Fig. 4A), food resources (rainfall, Fig. 4B) and air temperature (Fig. 4C).
We believe the results of this study were unlikely to be affected by any unrecognized cases of extradural spinal tumor in this analysis.
Such trials might be systematically different from trials that were included, although the variation observed in this study is unlikely to be affected by the inclusion of a small number of additional trials.
The fracture mode of the steels studied is found to be affected by the presence of notch, which is also attributable to these causes.
If results of tracing studies are likely to be affected by selection bias, correction of mortality is again best done in sensitivity analyses, using a range of plausible values.
On balance, these data issues suggest that under-estimation is more likely than overestimation, and that the major conclusions of this study are not likely to be affected by any of the data uncertainties.
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