Sentence examples for study the turnover of from inspiring English sources

To study the turnover of the endogenous optineurin, RGC5 cells were treated with 5 µg/ml of cycloheximide for 4 h to block the protein synthesis, and were chased for 0, 2, 4, 6, 8, and 24 h.

To study the turnover of the overexpressed optineurin-GFP, the low and the high expresser clones were induced by Dox for 20 h, treated with cycloheximide, and chased for 0, 4, 8, 16, 24 and 40 h.

To directly study the turnover of the proteins involved, cycloheximide was injected in rats to block synthesis of new proteins.

To directly study the turnover of the corresponding messages, the transcription blocker actinomycin D (ActD) was injected.

To seek mechanistic explanations for the observed differential gene regulation, it was reasonable to study the turnover of specific histone PTMs at selected gene promoters.

Even though this number is derived from studying the turnover of cardiomyocytes in mice, it correlates very well with the proposed rate of annual cardiomyocyte self-renewal (0.5percentto1percentcenthathat Bergmann and colleagues estimated for the human heart in a 2009 paper published in Science.

To examine whether Abi-1 dynamics indeed reports back on the turnover of the entire WAVE complex, we also studied the turnover of WAVE2.

In fact, about 150 fat cells wink out of existence every second of the day in a typical body, says Kirsty Spalding, a cell and molecular biology professor at the Karolinska Institute in Sweden and lead author of a recent study on the turnover of fat cells.

A study evaluating the turnover of adhesion components in randomly migrating cells implicated p130Cas in regulating FA disassembly, with the apparent rate constant for FA disassembly ∼19-fold lower in Cas −/− MEFs as compared to cells expressing wild type (WT) p130Cas [25].

While studies on the turnover of chromatin modifications that may be involved in memory are in their infancy, an exploration of his model in the light of modern epigenetics produced somewhat surprising results.

Using Cortactin, an established invadosome marker, we were able to study the turnover rates of the invasive structures in trophoblasts.