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To study the target of benzimidazole carbamate drugs against Cysticerci cellulosae and give a theoretical basis for type evolution and new drug design, the changes of key enzyme activities and metabolite contents in the pathway of energy metabolism in C. cellulosae in vitro and in vivo were tested with albendazole and oxfendazole, respectively.
TH made several of the transgenic constructs used to study the target of dopamine neurons in ascidian sensory vesicle, and to perform co-localization studies, supervised by YS.
In our previous study, the target of miR-130b was found to be peroxisome proliferator-activated receptors (PPAR), which disrupt TGF-β signaling through an anti-fibrotic signaling mechanism [73,74].
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To identify synaptic vesicle targeting sequences and to follow the path that proteins travel en route to the synaptic vesicle, we have used a defective herpes virus amplicon expression system to study the targeting of a synaptobrevin-transferrin receptor (SB-TfR) chimera in cultured hippocampal neurons.
Further investigation is warranted to study the targeting of SOCS6 to mitochondria.
Thus in this setting, DNA methyltransferases are introduced into hypomethylated cells, and are therefore an ideal model to study the targeting of de novo DNA methylation.
The characterization of POF targeting to PoX1 and PoX2 in females thus provides a unique opportunity to study the targeting of POF to a nonheterochromatic target and to further our understanding of the evolution of these two targeting systems.
To keep the immune response under control, hosts have evolved regulatory pathways that should be considered when studying the target of the selection pressures acting on immunity.
We studied the target proteins of artemisinin in Trypanosoma brucei brucei using the affinity-labeling method.
We further studied the target genes of the miRNAs by degradome library sequencing.
31 In this study, the targets of the intervention are the services.
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