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To study the mutations in codons 12 and 13 of the KRAS gene were carried out separate PCR reactions for each codon, using 100 ng of genomic DNA.
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To study the mutation in these two types of vegetables induced from spaceflight, we flew the seeds on the 20th Chinese recoverable satellite which orbited the Earth for 18 days.
Of relevance to our study, the mutation in the nicotinamide nucleotide transhydrogenase gene which causes insulin deficiency in C57BL/6 mice [29] was not found in our C57BL/6 colony (data not shown).
Mechanism study about the mutations in PML-RARA for AS2O3 resistance indicates that higher dosage of AS2O3 or the combination of AS2O3 with chemotherapy might be helpful for those patients harboring A216T mutation.
Analysis of the number of tdTomato-positive cells present in the different cortical layers showed a significant difference between the four different conditions (two-way repeated measure ANOVA, effect of interaction: F(27,180) = 13.73, p < 0.0001), consistent with our previous in vitro and in vivo studies that the mutations in RHEB are gain-of-function hyperactivating mutations.
The fever closely resembles certain periodic fevers that humans inherit, and studying the mutation in the dogs could help human geneticists develop treatments.
The study of the mutation in primates illustrates our phylogenetic history.
It was established in this study that the mutation in rosR did not affect the genome structure or RNA processing (COGs A and B).
We chose to study the mutation process in P. fluorescens for three reasons.
To do this, scientists study the effect of the mutations in cancer cell lines and animal models of the disease.
But all the mutations in the study–even those shared among cancers occurred at low frequencies, suggesting that the search for cancer genes may be more difficult than researchers had hoped.
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