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In the same study, the disruption of the PfRH2a gene did not produce any differences in invasion phenotypes between the knockout and wild type parasites, implying that PfRH2a does not play a primary role in this invasion pathway [16].
In the present study, the disruption of foeto-endometrial connection as a result of contraction of the uterus caused by the pulsatile release of the endogenous PG metabolite could be the possible cause for the occurrence of foetal deaths within 24 to 48 hours after cloprostenol injection.
Previous studies have linked decline in the expression of CREB to a progressive increase of apoptosis [ 42], and in one study the disruption of CREB1 expression in mouse forebrain, resulted in progressive neurodegeneration in the hippocampus and in the dorsolateral striatum [ 43].
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Additionally, in a growing resting state fMRI studies the disruption of functional connectivity networks in epilepsy have been reported [32], [33].
Although it has been shown that individual microRNAs may regulate multiple genes, the current knowledge for microRNA::mRNA regulation has been largely obtained from the studies of the disruption of microRNA::mRNA interactions on a single gene basis.
So, we study the effect of disruption in the links transmitting loads among node pairs in a hub network.
First, given that invasive ductal carcinoma is the most common type of breast cancer, we want to study the formation and disruption of ductal morphogenesis.
To study the correlation between disruption of the ESAT-6 CFP10 ESAT-6 CFP10and interactionression levels of HCL2, andArabinose gradient liquid β-Galactosidase assay was performed.
The method of light scattering is general and can also be used to study the formation or disruption of macromolecular complexes other than the ribosome.
Results from the present study demonstrated that the disruption of pflB gene limits the regeneration of NAD+ to a greater extent compared to the disruption of ldhA gene in strain NZN111.
It is likely that the release of the viral glycoproteins – gp120 for HIV-1 [8] and gD/B/H for HSV (this study) – results from the disruption of the integrity of the viral membrane.
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