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This newly developed, defined in vitro model was used to study the differentiation of fetal rat skeletal muscle and it promoted the formation of myotubes from the dissociated rat fetal muscle cells.
Some of the researchers at the centre will study the differentiation of stem cells into other cell types, one group by using human embryonic stem cell biology and another by studying early embryo development.
These cells differentiate rapidly, form contractile myotubes, express characteristic marker genes and, therefore, serve as a bona fide in vitro model to study the differentiation of myoblasts to myotubes [25].
Recently, codon usage has also been investigated to study the differentiation of mitochondrial PCGs [ 12].
These cells are usually employed to study the differentiation of myoblasts and osteoblasts.
In this study, the differentiation of pre-OC murine macrophage-like RAW 264.7 cells into multinucleated OCs was stimulated using recombinant RANKL protein.
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C2C12 cells are a useful tool for studying the differentiation of myoblasts and osteoblasts, expressing various proteins, and exploring mechanistic pathways.
Trappmann et al. studied the differentiation of hMSCs and human epidermal stem cells using collagen coated polydimethylsiloxane (PDMS) and polyacrylamide (PAAm) hydrogel surfaces.
This study on the differentiation of single NMP progenitors generated by FGF2/CHIR treatment of EpiSC is a sequel to the previous study on lineage differentiation of these cells at the population level.
Taken together, these findings indicate that only a combination of PAX6, FOXC1, and SIX1 among the TF combinations examined in this study promoted the differentiation of hESCs toward LGE-like cells.
Current study encourages the differentiation of human endometrial stem cells into osteoblast-like cells using osteogenic media for potential bone tissue engineering purposes.
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