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Transmission electron microscopy (TEM) was performed as described in a previous study (Qin et al. 2013).
We further apply the guidelines for penalized regression developed from these synthetic data to real expression data and to penalized logistic regression for metagenomic data from the gut microbiomes and obesity status of subjects in the MetaHIT study (Qin et al., 2010).
En chun Pan and Qiu jin Xu designed the study; Qin Zhang, Lin fei Liu, and En chun Pan performed the study; Hong Sun, En chun Pan, and Xiao dong Chen analyzed the data; Hong Sun and En chun Pan drafted the paper.
Again, most of these methods work on up to some thousands of features (Parks and Beiko, 2010; Segata et al., 2011; White et al., 2009), with the notable exception of one study (Qin et al., 2012) where quantification and association testing was done for >4.3 million predefined genes.
However, a similar post-recombination-filtering displacement of strain 1,231,408 was not observed in a previous study (Qin et al. 2012), in which the authors used PHI (Bruen et al. 2006) to detect and remove recombination signals prior to phylogenetic tree building.
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Additionally, in some now classic studies, Qin and colleagues were able to generate regulatory cells by the administration of non-depleting anti-CD4 monoclonal antibodies in vivo to thymectomised mice (reviewed in [ 48]).
As milk consumption has been shown to be positively associated with prostate cancer risk in previous case-control and cohort studies (Qin et al, 2004, 2007), it is reasonable that drinking coffee with added milk or cream would afford less-effective protection.
> > To evaluate the performance of MetaCluster 5.0 on real dataset, the dataset provided by the study of Qin et al. in (Qin et al., 2010), which collected samples from the feces of 124 European adults, is studied.
In the study by Qin, the role of HDAC4, a member of Class II HDACs, was investigated in an in vitro model.
Furthermore, in the large epidemiological study by Qin et al., patients with localization related epilepsy were only slightly over-represented among those who were psychotic and this difference fell short of statistical significance [ 29].
In 2014 and 2015, Zhang and Qin studied the stability of Runge-Kutta methods [21] and one-leg methods [22] for this kind of problems, respectively.
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