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While a shift in food desire ratings was observed following sleep deprivation, the controlled eating schedule of the study precluded the ability to measure actual changes in caloric intake under ad libitum (rather than controlled) food availability.
Limitations: The cross-sectional design of this study precluded causal analysis of reported associations and some retrospective assessments are error-prone because of recall bias.
The retrospective nature of this study precluded doing so.
The limited number of patients in our study precluded assessing the individual effects of distinct molecules within the fluoroquinolone class.
The large number of participants in this study precluded the use of MSLT for more comprehensive assessment of daytime sleepiness.
Though the small size of the study precluded our ability to test statistical significance, these results are consistent with selection for virus with shorter variable loops and fewer glycosylation sites during transmission of HIV-1 subtype C in other settings.
The retrospective nature of the study precluded the use of creatinine clearance as a more optimal measure of renal function and did not allow differentiation of infection-related or AKI-induced mortality.
In this context, the retrospective nature of our study precluded a reliable analysis.
The modest number of deaths in the study precluded multivariable logistic regression analysis with more than 2 3 independent variables [34].
However, the limited sample population of entecavir-treated patients in our study precluded us from testing the relationship between HBeAg and Treg/Th17 ratios.
By its nature, the study precluded blinding.
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