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Conversely, if the estimated variance is too large (pilot study overly conservative), power will be under-estimated.
There is a concern that the distance between the RFC loading site and the biotin-avidin block used in this study overly restricts the degree to which the released PCNA can truly dissociate from RFC.
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Traditional studies overly simplified the signaling systems into cascades of events that by no means can reconcile the complex dynamics of living systems.
Kraemer, et al. [ 1] noted that if the estimated variance is too small, i.e., when the pilot study is overly favorable, power will be over-estimated.
But she joined several peers in saying that mail and phone solicitation would almost certainly leave the study group overly weighted with people with fewer cognitive problems.
Ironically, Romney has made a similar mistake to the one the Obama Administration made in early 2009, when two of Obama's economists released a study with overly optimistic unemployment projections.
Those who criticize the committee study for overly focusing on the past should understand that its findings directly relate to how the CIA operates today.
But the MPAA challenged the methodology of the USC analysis, saying the study uses overly broad, aggregated data that paint an imprecise and inaccurate picture of employment trends in film and TV production.
Although he found it lacking a "centerpiece track", Capobianco ultimately praised the album as a "funk" departure from most of the contemporary soul he found "studied and overly reverent".
We deem this an important finding because it is likely that the results presented in these studies are overly optimistic [41] and may not be reproducible in other patient populations.
Often studies are overly generic, with little acknowledgement or identification of crucial features that make for important cultural distinctions.
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CEO of Professional Science Editing for Scientists @ prosciediting.com