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In this study, offspring mice were immunized via i.n. in order to induce a better protection in the respiratory tract.
Indeed, in the current study, offspring from obese dams consumed more when they were fed either chow or HFD.
In the present study, offspring of nutritionally challenged dams develop obesity; thus a perpetuation and possibly a compounding of accelerated pubertal onset may ensue in the next generation as these offspring will themselves be fatter at an earlier reproductive age.
Furthermore, it is plausible that this epigenetic state could be transmitted via his sperm to the study offspring.
Study offspring of male Gulf War veterans numbered over 30,000 and of females Gulf War veterans nearly 4,000.
In the prospective study, offspring adiposity was assessed by skinfold thickness from birth to age 24 months.
Similar(44)
For comparison with another model of programmed hypertension we studied offspring of mothers treated with dexamethasone during pregnancy.
36 37 Studying offspring at younger ages cannot reliably identify those who will ultimately become obese.
We studied offspring mortality according to time of follow-up (0-6 dafterfter birth versus later).
In each of the adequate studies, offspring effects occurred only at doses that also caused maternal toxicity.
To date, animal studies investigating the effects of maternal overnutrition on metabolic disease in offspring have studied offspring at 3 mo of age and older.
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CEO of Professional Science Editing for Scientists @ prosciediting.com