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He said continued monitoring was beginning to suggest that more serious lung problems might follow; he will complete a new epidemiological study of responders in a few months.
In this large study of responders to a health status questionnaire there was a slight increase in the percentage of participants consulting primary care following the survey.
Supporting its role as a regulator of IFNβ-induced genes, an intronic SNP in STARD13 was amongst eighteen that were replicated in a study of responders to IFNβ therapy in MS patients [ 56].
Moreover, in a retrospective case-controlled study of responders to DTIC or TMZ, it was found that responders to TMZ developed significantly less CNS relapses than responders to DTIC (Paul et al, 2002).
For example, one study of responders to a US patient satisfaction survey that involved nearly 20,000 patients in 76 hospitals [ 8] found significant differences between the first 30% of responders and the remainder of responders on nine out of thirteen scales.
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A pilot study of responder analysis in a single trial indicated that it might be a useful way of reporting pain results in osteoarthritis.
Table 1 shows the socio-demographic and clinical characteristics of the study sample of responders.
Haplotype frequencies were reconstructed in the study population of responders and non-responders.
In the present study, 25% of responders assessed their relationship with intensivists at a score < 35 of 100.
In this study, 73% of responders had an Arg/Arg genotype and three were heterozygous, but 66% of non-responders showed a Gln/Gln or Gln/Arg genotype (P=0.038).
This paper showcases the usefulness of using a mixed-method focus group study of first responders to examine the design of a hand-held radiation detector.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com