Sentence examples for study of mutations in from inspiring English sources

We utilize this approach to conduct a study of mutations in the EGFR signalling, motivated by a paper from Klinger et al. (2013).

The study of mutations in human genes is nevertheless of paramount importance for understanding the pathophysiology of inherited disorders, for optimizing diagnostic testing and guiding the design of emergent therapies.

Our genetic approach is the study of mutations in a critical adapter molecule, LAT.

We investigated the biological validity of these observations in a genetic study of mutations in some of these genes.

A further study of mutations in the tyrosine phosphatase gene family identified 6 putative tumour suppressor genes that were mutated in 26% of the colorectal cancers analysed [3].

We here describe a study of mutations in the tetranucleotide marker D7S1482 in cells obtained by mouth rinse in a case control study for head and neck cancer.

Such a finding would be unprecedented and did not occur in a detailed study of mutation in Salmonella populations evolved in the absence of selection (Lind and Andersson 2008); however, it would explain the simultaneous increase in both d N and d S with distance from replication origins.

Recent studies of mutations in multiple myelomas revealed that NIK, or more frequently proteins such as TRAF3 and cIAPs that control NIK degradation, are targets for mutation in these tumors [13], [14].

Future studies of mutations in the rps13 promoter using a luciferase reporter may be useful in clarifying the importance of these bases in both of its TRP2 elements in enhancing transcription.

A literature review was undertaken to identify data for standard in vivo efficacy studies of SP in children under the age of 5 years and studies of mutations in dhfr and dhps genes conducted in locations near to the above trials in time and place.

Further studies of mutations in NSCLC are warranted to facilitate more specific diagnoses and guide treatment.