Exact(10)
Thereafter, oral information was provided on an ongoing basis before each study occasion.
Thirteen patients were studied on the first study occasion only, and seven were studied twice.
Tolerability was assessed daily by the clinician during each study occasion (using an adverse-event report form) and at the follow-up visit 1 week after last study occasion (using an adverse-event report form and laboratory assessment).
Using the best and worse TEM per observer or study occasion we calculated 95% confidence intervals (CI) [ 18, 23, 24].
Subjects were randomly assigned to partial sleep deprivation on either the second (n = 4) or third (n = 5) study occasion.
The study was started before repeated measurements were routinely used for the diagnosis of type 2 diabetes, and blood glucose was therefore measured only once per study occasion.
Similar(50)
Individual pharmacokinetic parameters can change between study occasions (Supplementary Data online).
Hyperinsulinemic euglycemic clamp studies were performed the day after the second and third study occasions.
Weight did not differ between groups or study occasions (P > 0.05) (data not shown).
For the liver, voxel sites were matched at the study occasions.
A cross-over study design requires that the subject is in a similar state at both study occasions.
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