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There were existing networks also in the case study municipalities.
Evidence is gathered from two case study municipalities, Oeiras and Cascais, that have applied this indicator set, through a review and analysis of documents and semi-structured interviews with relevant public officers.
There were no statistically significant differences in the results of the essential laboratory tests between the study municipalities (Table 1).
For 123 study municipalities, covering 78.5% of the total study exposure-years, we obtained annual average THM levels.
This study protocol for a block randomized, controlled, exploratory trial randomly assigns study municipalities in Mexico to be audited by federal auditors, by state auditors, and a control outside the national program of audits.
All children were seen within 30 minutes of arrival by a study nurse who screened whether the patient's age (6 weeks to 23 months), residency (six study municipalities) and symptoms met the criteria for data collection.
Owing to logistical limitations, we discontinued follow-up of subjects who emigrated from the study municipalities, and as a result 22 subjects (2.5% of the analytic cohort) were lost to follow-up during the study period.
For inclusion in our study, municipalities had to have carried out both breast and cervical cancer screening in 2007 and 2008, and not have merged with another municipality during the period.
In this study, municipalities of residence were available for the whole residential history, but only the last address was complete and could be geocoded, which might be a source of misclassification if the relevant exposure period is prenatal or during early childhood.
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All participants included in the CM intervention had been recruited from a nearby university hospital, from the four primary care centres in the study municipality, through the municipal home care organisation or by the participants contacting the research group by themselves.
The participants were recruited from a university hospital (n = 20), from primary care centres in the study municipality (n = 117), through the municipal home care organisation (n = 13) or because they contacted the research group (n = 3).
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