The main limitation of our study is insufficiency of result generalization at the population level.
Recruitment ended prematurely before target enrollment number (n=85) was reached, since the study underwent insufficiency of subjects who fulfilled the strict inclusion criteria.
In our study, renal insufficiency groups (Group III and IV) had higher composite MACE occurrence and mortality after a 12-month follow-up as compared with groups with no renal insufficiency.
As retrospective study, the insufficiency of the socioeconomic and environmental information, such as the crashes scenario, including road conditions, vehicle speed, full-face helmet, cord-injury symptoms, was considered as limitation in our study.
Although in our study, adrenal insufficiency frequency (77.6%) was similar to the results of both studies cited above [ 19, 20], no significant difference was noted in the frequency of vasopressor weaning of brain-dead patients compared to plasma cortisol level at baseline or to initial response to ACTH stimulation.
The following social factors were significantly associated with MDD in this study: food insufficiency, being HIV positive, poor social support, increasing number of negative life events, increasing life events stress scores, increasing number of reported war trauma events and increasing war trauma events stress scores.
Blacks have a higher preterm birth rate compared with Whites, and since having a preterm delivery is in itself a risk factor for cervical insufficiency, this study examined cervical insufficiency among primiparous women to determine if there are ethnic and racial differences in cervical insufficiency risk.
General reasons for discrepancies between studies are insufficiency of sample size, age/gender/BMI/ethnic/racial differences, differences in prevalence of infectious agent in case and control groups, differences in immune response caused by specific ligand, differences in stratification, methods of diagnostics of cancer or chronic inflammatory conditions, genotyping methods, and chance.
On the other hand, we confessed that our study contained some insufficiencies to investigate the associated mechanisms underlying MMR-deficiency in cervical carcinoma.
Despite undertaking the precautionary measures, a subsequent study suggested the insufficiency of the deletion of the APOE gene information to prevent a risk prediction for LOAD: "the deletion of the APOE gene information only may not prevent accurate prediction of Dr. Watson's risk for LOAD conveyed by APOE risk alleles.
