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All codes and definitions were established prior to study initiation.
The timing was dictated by regulatory requirements in Belgium at the time of the study initiation.
Patients had been diagnosed with EoE for a mean of 37.6 months before study initiation.
Before study initiation, the animals were accustomed to laboratory conditions for 2 weeks.
Approval was obtained from the Cincinnati Children's Hospital Institutional Review Board prior to study initiation.
As study day 1 was defined the day of study initiation.
The margin of safety was evaluated in Beagles, which were 6 weeks old at study initiation.
All approvals were granted prior study initiation.
The DMC met once prior to study initiation.
The first visit took place within 6 months of study initiation.
None of the patients reported opportunistic infections up to 1 year before study initiation.
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