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However, the statistical power is still lower than 70% even when there are 120 studies (200 patients in each study) in the trial network.
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The new clinical study adds questions about the effectiveness of stenting to the safety debate, at least in the patients studied in the trial, named Courage, for Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation.
A qualitative sub-study in the trial consisted of telephone interviews of participating patients about their experiences in the study.
Previous or current health condition not studied in the trial.
They are likely to exhibit a degree of homogeneity, which may influence the measure studied in the trial.
Despite the improved precision, additional confirmation was considered necessary given the extrapolative nature of our inferences about doses below the lowest dose studied in the trial.
When there are singleton studies in the trial network, the frequentist based random-effects model has relatively larger type I error than the Bayesian random-effects model.
AE are any clinical change, disease or disorder experienced by the participant during their participation in the trial, whether or not considered related to the use of treatments being studied in the trial.
Several novel therapeutics are also being studied in the trial setting in combination with radiation, including EGFR inhibitors [ 69], HER-2 inhibitors [ 70], and poly (ADP-ribose) polymerase inhibitors [ 71].
Many of the cities studied in the trial conducted by Brown and coworkers [ 17] had excellent response intervals and greater than average survival rates, thus indicating a relative 'best case' scenario.
The last study visit in the trial was August 6 , 1979 when all study medications were discontinued and treatment assignment was revealed.
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