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Our study has been constrained by the availability of transcriptional data sets publically available on a coherent microarray platform (the integration of data sets deriving from different technologies would have introduced too much noise in the meta-analysis).
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For years the scale of blood transcriptional studies has been constrained by the cost of the technology.
However, the robustness of the latter studies has been constrained by the lack of use of theoretical frameworks which would have helped in providing more rigorous accounts as to the behaviours of the actors involved in the delivery of aid.
However, most studies have been constrained by cross-sectional designs that limit causal inference due to failing to establish temporal order of exposure and disease.
For this reason, most synthetic peptide studies have been constrained to relatively short (no longer than the low 40s) polyQ repeat lengths and truncated C-termini.
To date, the study of nonadherence has been constrained to clinical studies.
For these reasons, bacterial phylogenetics has been constrained to studies of specific genes or to cultured organisms, which represent a small and biased portion of the bacterial tree of life.
High lithium-ion-conducting Li7La3Zr2O12 (LLZO) ceramic-based solid electrolytes have been intensively studied recently, but their widespread commercial deployment has been constrained due to their fragility and brittleness.
Study findings revealed that IMCI implementation in Matiari district has been constrained by numerous factors.
Dr. Hare, now an associate professor at Duke, has continued to probe the canine mind, but his research has been constrained by the number of dogs he can study.
But the movement has been constrained.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com