A previous study generated mice with a conditional deletion of TGFBR2 in COL2A1 expressing cells and found defects in the cranial base and vertebrae [ 36].
In order to address the question, we conducted a simulation study, in which 10,000 pseudo studies were generated, with each study having a sample size of 50, 100, 200, 300, 400, 500, and 1000 women.
ATG and DGH conceived of the study, generated crosses, and assisted with data analysis and manuscript revision, TD assisted with methodology and manuscript revision, and BSH participated in the design of the study and manuscript revision.
In addition to the DHQase kinetic diversities, this study generated a DHQase library with known catalytic constants that could be applied to design artificial modules of shikimate pathway for metabolic engineering and synthetic biology.
The 6185 SSR primers developed in this study generated 1458 loci, and with our previous data [ 8], a total of 2521 loci were applied to map construction.
A statistician who was not involved with the study generated a randomisation schedule using a computerised random number sequence.
A statistician not otherwise connected with the study generated the randomisation sequence by computer and supplied it in sealed opaque envelopes.
Detailed fluvial facies architecture realisations which are used in this study, are generated with a process-based approach utilizing geological data from the Lower Cretaceous Nieuwerkerk Formation in the West Netherlands Basin.
The molecular fingerprints used in this study were generated with the Java library jCompoundMapper developed by Hinselmann et al. [21].
All the datasets in this study were generated with the QuantiTect SYBR Green I enzyme formulation (Qiagen).
