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In the same study, deletion of hapA reduced the total protease activity to 10% of the wild-type level.
In another study, deletion of the APC gene in TECs, through expression of K14 driven Cre, resulted in a hypoplastic non-functional thymus with an abundance of K14K8DP TECs.
In the present study, deletion or mutation of amino acids A159 and K160, which are essential for the interaction of M protein with actin, is detrimental to the recovery of IBV from an infectious IBV clone due to a defect in late stages of the IBV replication cycle.
In this study, deletion lines of Triticum aestivum cv.
However, in another study deletion of CTA1 caused an increase in CLS.
In CF patients, we identified three heterozygous CNMs involving CFTR, including the smallest CNM identified in this study (deletion of exons 25 and 26, 1.4 kb).
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First of all, the technique can be applied to study deletions with known breakage sites only.
It should be noted that it is quite difficult to study deletions by FISH on FFPE cases [ 42, 43].
However, in our study, deletions in the pre-S1/S2 gene were observed similarly in the HCC group and non-HCC group.
The majority of the informative lines when initially selected with few markers (35) generally showed deletions for a single chromosome [ 15], but when characterized with more markers (641) in the present study, deletions for multiple chromosomes were detected (Fig. 1).
In these studies, deletion of Podocalyxin's NHERF docking site led to a modest reduction in apical Podocalyxin.
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