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In that study, conditional knockout of APC in the hematopoietic compartment led to rapid and dramatic hematopoietic failure; specifically, Apc-depleted mice experienced exhaustion of the myeloid progenitor pool.
The main purpose of the paper is to study conditional residual lifetime of coherent system, given that at a fixed time certain number of components have failed but still there are some functioning components.
In effect, the presence of structural changes in the series of conditional variances as detected via the ICSS algorithm heave motivated us to study Conditional Correlation Dynamics [26] in a second stage as a procedure to determine the contagion effect across markets.
The chief alternative to stable cell lines is to study conditional, inducible or knockout systems.
In a recent study, conditional Pax6 knockout mice (Pax6fl/fl; Emx1-Cre mutants; Pax6 cKO mice) in which Pax6 expression was completely and specifically abolished in the cortex and hippocampus were generated [53].
The present research is a further development to study conditional relational learning in ALS patients.
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In this work, we have performed a quantitative analysis of how allele frequency differences between populations affect the power of genome-wide association studies, conditional on a first wave of GWAS performed strictly in European samples.
Indeed, in a few African studies, conditional cash-transfer systems have been noted to reduce risky behaviours in girls (30– 30).
In contrast, our work focuses on studying conditional and time-dependent behaviours or sequential dynamics of network modules, which are functionally enriched on specific biological processes [ 13].
However, when analyzing HRQL data in RCTs or cohort studies, conditional means rather than predictive densities are commonly of major interest [ 4].
In other studies, conditional mutagenesis has been used to assess the role of ciliopathy loci postnatally (Davenport et al., 2007; Haycraft et al., 2007; Song et al., 2007; Jacoby et al., 2009).
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