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In this study, compounds, b24 and b25 exhibited more anticancer potential (Table 24, Fig. 7) [33].
Fig. 1 Chemical structure of study compounds Pi (i = 1 6).
A mass balance indicated that ongoing transformation occurred for seven study compounds.
Generally, the study compounds exhibited affinity for both the A1 and A2A adenosine receptors.
From this study, compounds that 3 and 19 can be considered as promising multifunctional lead compounds.
The radiative lifetimes of the study compounds are from 7.61 to 7.11 ns and increases in the following order P4 < P1 < P2 < P5 < P3 < P6.
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Figure 3 Selection of study compound subset from the entire PubChem Compound database.
In this study, Compound 4 was used as a reference for docking studies.
Therefore, in this study, compound 5b was used as a lead compound for further optimization.
While biologists continue to study compound eyes, materials scientists such as John Rogers try to mimic elements of their design.
The results from the new study "compound our concerns," Cordray said.
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