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A soil microcosm fed with sterile distilled water was included in this study and considered as control.
Differences in dietary intake are analysed throughout the study and considered as possible covariates in all statistical analyses.
The acceptable error was compatible with the logistics of the study and considered satisfactory for a validation study.
Moreover, the compliance of patients to the proposed diet will be registered in a patient notebook throughout the study and considered in the statistical analysis.
If fulfilled, the individuals will be retained in the study and, if not, will be transferred out of the study, and considered a screening failure.
The Institutional Review Board at Brigham and Women's Hospital approved this study and considered completion of the questionnaires to be informed consent.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com