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In a recent study, amendment of nutrient solution with potassium silicate has reduced the anthracnose disease of Capsicum variety Awlegama by over 75%% (Jayawardana et al. 2014a).
I believe the vast majority of people who study Amendment 62 will find it complicated, dangerous, occasionally ridiculous--and something we have seen before.
The PRN committee gave ethical approval for this study (amendment on application 11.36).
The rationale behind this study amendment will be described further in the discussion.
Extensive cardiac safety assessments were subsequently implemented through a study amendment.
Addition of group C to the study would be the matter of a separate study amendment.
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It was also not clear whether additional information from all study amendments had been located.
NW recruited, assessed and managed the ongoing care of patients; contributed to study amendments; was involved in data analysis; presented early outcome data to an international conference.
Important study amendments included premature termination of the trial owing to slow recruitment and change of primary efficacy variable to response based on Investigator's Global Assessment (IGA) instead of overall scaling score.
In this study an amendment to the protocol increased the inclusion limit for cholesterol.
The study and amendment were reviewed and approved by all sites and Research Ethics Boards, and all subjects provided written informed consent.
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