However, the Bayesian coalescence approach implemented in this study ameliorates these problems by achieving improved accuracy and more thorough genealogical sampling [47].
Thunderstorm simulation in the laboratory setting induces fearful and anxious behavior in beagles, most notably manifested by increased inactivity ("freezing"), which, in a companion study, was ameliorated by the anxiolytic diazepam (Araujo et al., 2009).
In this study, valsartan ameliorated the inflammatory milieu in liver, resulting in enhancement of insulin action.
In this study, TEA ameliorated the sepsis-induced increase in microvascular liver blood flow and attenuated leukocyte recruitment.
However, in that study pioglitazone ameliorated other risk factors beyond blood glucose; a post hoc analysis suggests that HDL could have been a more important mediator of cardiovascular benefits than HbA1c (22).
In the present study, Piwep ameliorated the severity of the EAE in MOG-injected mice, which was accompanied with reduction of demyelination, attenuation of microglia activation, and inhibition of infiltrating encephalitogenic immune cells.
In our study, CAPA ameliorated the I/R injury, but this protective effect disappeared when the –OH functional groups were substituted with methoxyl groups, and the antioxidant activity of CAPA may contribute to the protective effect on the I/R injury and cardiac dysfunction in diabetes.
When this heavy slant towards the mass spectrometry studies is ameliorated by requiring the interactions to be identified by three different studies (meaning that at least one of the studies must use a method other than mass spectrometry), both the bias towards counting more interactions for abundant proteins and the tendency of interactive proteins to evolve more slowly disappear (Table 1).
The study also indicates that the design of the study could be ameliorated in several ways.
For example, in one study SphK1 inhibition ameliorated angiotensin II-induced acute hypertension [ 76] and in another study deregulation of specific S1Ps played a role in cardiac microvascular dysfunction [ 77].
