Therefore it cannot be excluded that it may be possible to demonstrate a decreasing effect of the D4 antagonist – in the doses employed in the present study – on alternation rate, using another spontaneous alternation paradigm.
In the present study, spontaneous alternation behavior in scopolamine treated rats was significantly lower than in rats treated with vehicle.
In this way, the researcher will be able to study the alternation or synchronism among all these sets of coexpressed genes.
Here we studied the alternation of MCF structure and potential correlated functions of MCF during metazoan evolution.
Randomized controlled clinical trials or quasi-randomized studies (using alternation, date of birth, patient identification number, weekday).
5 A few of the well designed studies (randomisation, alternation) comparing individuals who were or were not vaccinated with BCG looked at the effect on mortality associated with tuberculosis and all cause mortality.
Two of these studies alternately assigned participants [ 18, 19] which, since alternation is a non random "deterministic" approach [ 11], cannot be considered true randomisation.
Reported studies showed alternations of thyroid hormones in critical illness, mostly in adults and some in children.
The digital nature of RNA-seq technology coupled with powerful bioinformatics methods including Alexa-seq [ 25], IsoEM [ 26], Multisplice [ 27], MISO [ 28], Cufflinks [ 29, 30], iReckon [ 31] and RSEM [ 32, 33], which aim to quantify isoform expression accurately, provides the opportunity of systematically studying expression alternations at isoform level.
At a minimum, this implies that urethane induces a pharmacological condition that is similar to natural sleep and constitutes a good model system for the study of brain alternations during unconsciousness.
