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This is the first study aiming to define the diagnostic accuracy of the sense of alarm when applied to dyspnoea and thoracic pain.
To the best of our knowledge, this is the first study aiming to define the diagnostic accuracy of the sense of alarm when applied to dyspnoea and thoracic pain using the validated GFQ.
With these considerations, we initiated this phase I study, aiming to define the safety profile and to determine the maximum tolerated dose, the dose-limiting toxicity, and the recommended dose of docetaxel in combination with cyclophosphamide, without colony-stimulating factors, as first-line chemotherapy in patients with metastatic breast cancer.
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