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It was a rare kind of study: a "challenge" trial in which hexamethonium, a drug not currently approved by the Food and Drug Administration FDAA), was used to induce asthma-like symptoms in healthy subjects.
In a more recent study, a challenge dose that overcame NP DNA vaccine protection was similar to the amount used here [2].
A number of species distribution models (SDM) are available, making the selection of the most appropriate methodology for each case study a challenge [ 66].
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However, in many instances, the limited number of cells makes the application of this technology in tumour heterogeneity studies a challenge.
Exposure assessment that is applicable in longitudinal studies is a challenge when studying the modern technologies.
To have a homogeneous study population across different studies is a challenge in systematic reviews.
Matras's immaculately researched, warm and comprehensive study is a challenge belatedly to make a start.
Despite the warnings, the results of one study present a challenge to the notion that low levels of mercury have any negative effect.
Our recent study on a challenge of new materials for next generation's magnetic recording approaching an ultra high areal recording density beyond 1 Tbis/in.2 is overviewed.
Perhaps most troubling is that Darwin had no fewer than four main themes for his book, which he addressed throughout his study, providing a challenge for most readers.
This study poses a challenge to journalism.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com