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The limitations of these observational studies were underscored by Yeh et al, suggesting that in order to assess the clinical impact of DES, the comparison of a BMS period versus a DES period could be more reliable than comparing patients implanted with one or the other type of stent, in spite of complex statistical analyses.
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The validity of the OGTT-derived index AUCInsulin 0-30)/asCGlucose(0-30) as a preferable proxy for the assessment of β-cell function in large genetic studies is underscored by its strong correlation with IVGTT-derived AIR.
The importance of these pioneering studies is underscored by our brief summary of the key questions addressed by subsequent research into the mechanism of secretion.
The importance of such a feature for valid exposure assessment in epidemiologic studies is underscored by recent research to develop methods to identify utilities that have low spatial variability of DBP (Hinckley et al. 2005a).
Usefulness of this study is underscored by pointing out recent evidence suggesting that (1) air pollution in MCMA has larger health impacts than in similar cities located in developed countries, and (2) policies tackling air pollution in MCMA have had no impact on pollution levels.
The relevance of our study is underscored by the fact that small-molecule inhibitors of IAP proteins such as Smac mimetic are presently evaluated in early clinical trials.
The physiological relevance of the genes identified by the microarray study is underscored by the finding that at least eight downregulated genes have already been shown to be essential for normal spermatogenesis.
The translational relevance of our preclinical study is underscored as follows: This hypothesis-driven evaluation involves the rational combination of emerging treatment options for new targets, that is, the Bcl-2-inhibitor ABT-737 and the death receptor ligand TRAIL.
An interesting effect observed in this study is underscored by the "asymmetry" of the label thickness measurements in light of the wall thickness difference between labeled and control vein segments.
Moreover, the influence of social connectedness on health, as perceived by the participants in our study, is underscored in a recent survey of Mexican-origin farmworkers in rural northwest Oregon.
12 13 18– 20 The importance of our study is underscored by its analysis of data from a large multicentre cohort with clinically important outcomes and its comprehensive collection of variables from all three broad categories.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com