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The methods used in these prior studies were rather nonspecific and showed diffuse patterns of chromium throughout the cell [29].
Moreover, included studies were rather old and the review was restricted to studies carried out in the USA.
In fact, most studies were rather small [ 7, 9- 11] or limited to only one or two MMPs [ 7- 11].
The intra-assay and inter-assay coefficients of variation in these studies were rather good, ranging from 4%to14%4%to14%
In general, the original criteria in the reviewed studies were rather subjective and, thus, hard to interpret.
However, the sample sizes of most of those studies were rather small, thus the conclusions drawn from them are less convincing.
Similar(47)
Prospective randomized studies are rather scarce, particularly when considering the inclusion of untreated control population.
In addition, the algorithms used to predict performance in most of optimization studies are rather unsophisticated.
Studies in environmentally relevant conditions are necessary to better assess these parameters, but such studies are rather rare.
They are present in all organisms, but their origin is probably polyphyletic, so that MT evolutionary studies are rather scarce.
In most studies to date, however, there is a lack of empirical data at the individual level; the studies are rather cross-sectional designs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com