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Kevin McConway, professor of applied statistics at the Open University, said the conclusions from both studies were much the same – that the drug reduces the length of a flu bout.
Too much beta carotene can also be a problem: Controlled trials have shown that high doses increase lung cancer incidence and mortality among smokers and male asbestos workers, but the amounts tested in those studies were much larger than those in multivitamins.
Although the count variable approach does not test hypotheses about interactions between psychosocial problems, these studies were much more likely than others (14/31 [45%] vs. 0/9 [0%]; χ2 = 6.25, P = 0.01) to incorporate language about "synergy" or "interaction" that was inconsistent with the statistical models used.
Selection criteria for expectant management in previous studies were much stricter.
The mortality rates in these studies were much lower than prior studies, and this has led to speculation that the early aggressive volume resuscitation instituted in these studies partially explains this observed lower mortality.
These three studies were much different from our research for two reasons: the use of diverse classification criteria in the first study; in general, the different study designs, with the lack of relations among BDNF levels, clinical markers of disease severity, and the patients' BDNF genotype.
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Recent independent studies are much more skeptical about the decrease in violence.
But the typical level found in field studies was much lower.
For environmental exposures such as contact with volatile organic compounds, these studies are much rarer.
Replication of empirical studies is much more than a tool to police the field.
Church's studies are much, much more than that; they are often crowded with detail and finished in the same way that a painting may be.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com